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Curriculum Vitae
Michael Frotscher

Institute for Structural Neurobiology
Center for Molecular Neurobiology (ZMNH)
University Medical Center Hamburg-Eppendorf (UKE)
Falkenried 94
20251 Hamburg
Email:
 

Education and Professional Experience

Since May 2011 Hertie Professor for Neuroscience, Center for Molecular Neurobiology Hamburg (ZMNH), Institute for Structural Neurobiology (ISN)
1989-2011
Professor of Neuroanatomy, Inst. of Anatomy & Cell Biol., Univ. of Freiburg
1983-1989
Associate Professor (C3), Inst. of Anatomy, Univ. of Frankfurt/Main
1985
Visiting Professor, Dept. of Obstetrics & Gynecol., Yale Univ, New Haven
1982
Assistant Professor (C2) Inst. of Anatomy & Cell Biol., Univ. of Heidelberg
1981
Habilitation, Univ. of Frankfurt (advisors: Prof. R. Hassler, Prof. H. Braak)
1979-1981
Research Fellowship, Max Planck Inst. for Brain Research, Frankfurt/Main
1974-1979
Scientific Assistant, Inst. of Anatomy, Humboldt University, Berlin
1974
Postdoc, 1st Dept. of Anatomy, Semmelweis Univ., Budapest, Hungary
1974
Dr. med., Humboldt University, Berlin (advisor: Prof. W. Kirsche)
1966-1973
Study of medicine, Humboldt University, Berlin

Research Fields

Development and plasticity of hippocampal connections, neuronal migration, structure and function of central synapses.

Activities in the scientific community, honors, awards

2013 Jacob Henle Medal of the University of Göttingen
2011 Fellow of the American Association for the Advancement of Science
2009 Dr. honoris causa, Univ. of Frankfurt/Main
2009
DFG Senate for SFBs
2007
Hertie Senior Professor for Neuroscience
2007
Senator, Section of Neuroscience, German Academy of Sciences Leopoldina
2006
Dean for Research, Medical Faculty, Univ. of Freiburg
2004
Vize Chairman, Neuroscience Panel, DFG
2002
Ernst Jung Award for Medical Research
2001
Research Prize of Baden-Württemberg
2000
Max Planck Award for International Cooperation
1999
President of the German Anatomical Society
1998
Feldberg Award (Feldberg Foundation for Anglo-German Scientific Exchange)
1995
Member of the German Academy of Sciences Leopoldina
1995
Coordinator SFB 505
1993
President of the German Neuroscience Society (NWG)
1993
Leibniz Award of the Deutsche Forschungsgemeinschaft (DFG)
1992
Wolfgang Bargmann Prize
1992
Coordinator SFB 325

Editorial Boards (present and past):

J Neurosci, J Comp Neurol, Neuroscience, Eur J Neurosci, Exp Neurol, Hippocampus, Exp Brain Res, Restor Neurol Neurosci, Cell Tiss Res, Anat Embryol, Cells Tissues Organs, Neuroforum, Adv Anat Embryol Cell Biol, Brain Structure and Function, Frontiers Neurosci

Ten most important publications

  1. Studer D, Zhao S, Chai X, Jonas P, Graber W, Nestel S, Frotscher M (2014) Capture of activity-induced ultrastructural changes at synapses by high-pressure freezing of brain tissue. Nature Protoc 9:1480-1495.

  2. Hellwig S, Hack I, Kowalski J, Brunne B, Jarowyj J, Unger A, Bock HH, Junghans D, Frotscher M (2011) Role for Reelin in neurotransmitter release. J Neurosci 31:2352-2360.

  3. Frotscher M (2010) Role for Reelin in stabilizing cortical architecture. Trends Neurosci 33:407-414.

  4. Chai X, Förster E, Zhao S, Bock HH, Frotscher M (2009) Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. J Neurosci 29:288-299.

  5. Förster E, Zhao S, Frotscher M (2006) Laminating the hippocampus. Nature Rev Neurosci 7:259-267. Förster E, Tielsch A, Saum B, Weiss KH, Johanssen C, Graus-Porta D, Mül­ler U, Frotscher M (2002) Reelin, Disabled 1, and beta1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc Natl Acad Sci (USA) 99:13178-13183.

  6. Förster E, Tielsch A, Saum B, Weiss KH, Johanssen C, Graus-Porta D, Mül­ler U, Frotscher M (2002) Reelin, Disabled 1, and beta1 integrins are required for the formation of the radial glial scaffold in the hippocampus. Proc Natl Acad Sci (USA) 99:13178-13183.

  7. Vida I, Frotscher M (2000) A hippocampal interneuron associated with the mossy fiber system. Proc Natl Acad Sci USA 97:1275-1280.

  8. Markram H, Lübke J, Frotscher M, Sakmann B (1997) Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs. Science 275:213-215.

  9. Del Río JA, Heimrich B, Borrell V, Förster E, Dra­kew A, Alcántara S, Naka­jima K, Miyata T, Ogawa M, Miko­shiba K, Derer P, Frotscher* M, Soria­no E* (1997) A role for Cajal-Retzius cells and reelin in the development of hippocampal connec­tions. Nature 385:70-74. *equal contribution.

  10. Frotscher M, Heimrich B (1993) Formation of layer-specific fiber projections to the hippocam­pus in vitro. Proc Natl Acad Sci USA 90:10400-10403.