Job vacancies
Job Vacancies

Development and maintenance of the nervous system
Master/Diplom or MD student positions

in the group of ‘Development and maintenance of the nervous system’. We seek highly motivated young researcher with interest in neurobiology, molecular biology, biochemistry, genetics and/or electrophysiology.
There are several ongoing projects regarding the physiological function of dopaminergic neurons in the midbrain which can be picked up by master or diploma students. Dopaminergic neurons are altered in disease such as Morbus Parkinson and drug addiction. Our lab obtained exciting data from cell culture and unique transgenic mouse models suggesting a strong influence of cell surface receptors on the development and progression of these diseases which can be studied now in great detail.
The ZMNH offers an excellent environment to study neurobiological questions with a multitude of different techniques supported by a modern infrastructure and several service groups. Special benefits can be offered for foreign students.

Please send your application (preferentially by e-mail) to:
PD Dr. Edgar Kramer, ‘Development and maintenance of the nervous system’, ZMNH, Falkenried 94, 20251 Hamburg, Germany.
E-mail: ; Tel: 040 741055354; Fax: 040 741055359;
http://www.zmnh.uni-hamburg.de/zmnh/groups/kramer/kramer.html

Literature:

  • Kramer ER*, Knott L*, Su F, Dessaud E, Krull C, Helmbacher F, and Klein R (2006). Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 50: 35-47.
  • Kramer ER, Aron L, Ramaker GMJ, Seitz S, Zhuang X, Beyer K, Smidt MP and Klein R (2007). Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol. 5: 616-628.
  • Aron L, Klein P, Pham TT, Kramer ER, Wurst W, Klein R (2010). Pro-survival role for Parkinson’s associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol.  Apr 6; 8(4):e1000349.
  • Ertürk A, Mauch CP, Hellal F, Förstner F, Keck T, Becker K, Jährling N, Steffens H, Richter M, Hübener M, Kramer E, Kirchhoff F, Dodt HU, Bradke F (2011). Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nat Med. 18(1):166-71.

 

Studentische Hilfskraft gesucht

Die Servicegruppe “Transgene Mäuse” des ZMNH sucht dringend eine studentische Hilfskraft für ca. 30 Stunden/Monat.
Vorkenntnisse sind nicht erforderlich. Es wird sehr gründlich eingearbeitet!

Voraussetzungen:

  1. Freude am Umgang mit Mäusen
  2. Kein Kontakt zu Mäusen, anderen Nagern oder Nager-verwandten
  3. Bereitschaft zu Wochenendarbeit
  4. Zuverlässigkeit

Bei Interesse wenden Sie sich bitte an:
PD Dr. I. Hermans-Borgmeyer
e-mail:    hermans@zmnh.uni-hamburg.de
Telefon:  7410-56663

Doktorandenstellen (TV-L E13)

Am Institut für Neurale Signalverarbeitung, Arbeitsgruppe Ulrich Boehm, sind zwei Doktorandenstellen (TV-L E13) zu besetzen.
Die Arbeitsgruppe beschäftigt sich mit den neuronalen Schaltkreisen, die Reproduktionsphysiologie und -verhalten im zentralen Nerven-
system von Mäusen vermitteln. Hierzu sollen Mausmodelle entwickelt werden, die eine genetische Markierung neuronaler Schaltkreise
ermöglichen.
Literatur: Wen et al. (2010). Proc Natl Acad Sci U S A. 107: 16372-16377; Mayer et al. (2010). Proc Natl Acad Sci U S A. 107: 22693-22698; Mayer & Boehm (2011). Nature Neuroscience 14: 704-710.
Molekularbiologische Kenntnisse sind wünschenswert, aber nicht Voraussetzung. Interesse an neurobiologischer Forschung und
großes Engagement werden erwartet. Bitte richten Sie Ihre Bewerbung bevorzugt per e-mail an: ulrich.boehm@zmnh.uni-hamburg.de.
Für Rückfragen stehe ich gerne zur Verfügung.

 

Graduate Students (TV-L E13)

Positions available for two graduate students (TV-L E13) at the Institute for Neural Signal Transduction - Ulrich Boehm's group. We are
studying neural circuitry underlying reproductive behavior and physiology in the central nervous system. The goal of these PhD projects is
to develop mouse models allowing us to trace neural circuitry genetically.
Recent publications: Wen et al. (2010). Proc Natl Acad Sci U S A. 107: 16372-16377. Mayer et al. (2010). Proc Natl Acad Sci U S A. 107: 22693-22698; Mayer & Boehm (2011). Nature Neuroscience 14: 704-710.
Experience in molecular biology would be appreciated, but is not mandatory. Please send application preferentially by e-mail to: ulrich.boehm@zmnh.uni-hamburg.de. If you have any questions, please do not hesitate to contact me.

Dr. Ulrich Boehm, ZMNH, Institut für Neurale Signalverarbeitung, Falkenried 94, 20251 Hamburg. Tel.: 040-47105-5073; Fax: -6643 or -5102.
http://www.zmnh.uni-hamburg.de/zmnh/departments/pongs/boehm.html
Wir suchen
Medizinische Doktoranden/Doktorandinnen
zum nächstmöglichen Termin

Projekt: Wir untersuchen die elektrische Aktivität des unreifen Gehirns mit Hilfe elektrophysiologischer Methoden und wir korrelieren sie mit dem Verhalten junger Nagetiere
www.zmnh.uni-hamburg.de/zmnh/groups/hanganu
Aufgaben: Durchführung und Analyse der Verhaltensuntersuchungen an Mausmodellen der Schizophrenie
Voraussetzungen: gute Kenntnisse der Neurobiologie, Interesse an neurowissenschaftlicher Forschung, Teamarbeit
Die Durchführung des Projektes bedarf eines freien Semesters. Bezahlung als wissenschaftliche Hilfskraft (40-50 Stunden/Monat).
Ihre Bewerbung (CV, akademische Leistungen) richten Sie bitte an:

 

Department of Developmental Neurophysiology
Center for Molecular Neurobiology Hamburg (ZMNH)
University Medical Center Eppendorf (UKE)
Ph.D. position available

A PhD position is available at the Department of Developmental Neurophysiology, Center for Molecular Neurobiology Hamburg, Germany.

Our group investigates the synchronized patterns of electrical activity in the immature brain, their relevance for development of cognitive and behavioral abilities and their impairment associated with neurological disorders like perinatal ischemia and schizophrenia (Homepage.

The multidisciplinary project encompasses in vivo and in vitro electrophysiology, molecular biology, behavioral and pharmacological investigation. We offer a stimulating scientific environment in a dynamic, young and interdisciplinary team and state-of-the-art facilities. We guarantee extensive and individual training.

Applicants should have a strong background in neuroscience. Practical experience in electrophysiology and good programming skills (MATLAB) would be desirable. Fluent English is a prerequisite.

The position is available from August 2011 or later for 3 years.

Applications including (i) CV, (ii) a brief statement of expertise and interests, (iii) academic achievements, and (iv) 2 references should be sent to by email ( ).

Incomplete applications will not be considered.

 

Institute for Cellular and Molecular Cognition (IMCC)
Center for Molecular Neurobiology Hamburg (ZMNH)
University Medical Center Eppendorf (UKE)
Ph.D. student position available

We are offering a Ph.D. student position in a project assessing molecular mechanisms underlying an inherited neurodegenerative storage disease.
Experimental approaches will include mainly cellular, molecular, biochemical and histological analysis.
Experience in one discipline would be advantageous but not absolutely required.

For further information please contact:
Please send applications and curriculum vitae by e-mail or mail to:
Institute for Cellular and Molecular Cognition, ZMNH, Falkenried 94, D-20251 Hamburg.

The University of Hamburg seeks to increase the number of female scientists and encourages them to apply. Disabled people with equal qualifications are preferred.

In der AG Biosynthese Neuraler Strukturen des Zentrums für Molekulare Neurobiologie Hamburg sind zwei unbezahlte Praktikumsstellen für Studierende der Medizin im Rahmen ihrer Promotion zu besetzen.

Themenbereiche
1. Genetische Tiermodelle neurodegenerativer und psychiatrischer Erkrankungen
Methoden: Histologie, Immunhistochemie, Morphometrie, Verhaltensstudien
2. Adhaesionsmoleküle und Regeneration im peripheren und  zentralen Nervensystem
Methoden: Histologie, Immunhistochemie, Verhaltensstudien

The Research Group of Biosynthesis of Neural Structures at the Center for Molecular Neurobiology Hamburg has to fill two unpaid practical positions for medical doctors promotions.

Topics:
1. Genetic animal models of neurodegenerative and psychiatric diseases
Methods: histology, immunohistochemistry, morphometry, behavioral tests
2. Adhesion molecules and regeneration in the peripheral and central nervous system
Methods: histology, immunohistochemistry, behavioral tests

Zeitdauer / Duration: 9 – 12 Monate / 9 – 12 months
Projektleitung / Project Leader: Prof. Dr. M. Schachner Camartin
Betreuung / Supervision: Dr. I. Jakovcevski
Bewerbung / Application:
Lebenslauf und Zeugnisse an: / Curriculum vitae and recommendations to:

Prof. Dr. M. Schachner Camartin
AG Biosynthese Neuraler Strukturen
ZMNH Universität Hamburg
Falkenried 94
20251 Hamburg

Kontakt / Contact

Tel. (040) 7410 56288

The University of Hamburg seeks to increase the number of female scientists and encourages them to apply. Disabled people with equal qualifications are preferred.

Institute for Cellular and Molecular Cognition (IMCC)
Center for Molecular Neurobiology Hamburg (ZMNH)
University Medical Center Eppendorf (UKE)

Positions available for Bachelor, Master/Diploma, MD and Ph.D. students

We are looking for students interested in participating in projects assessing the functional role of activity-regulated genes in learning and memory and a variety of neuronal diseases, including addiction, depression, tinnitus and neurodegeneration. We are using mouse genetics for building bridges between molecular biology and systems biology. Several transgenic and knockout animal models, as well as brain-region specific knock downs are currently analyzed in molecular, biochemical, cellular and electrophysiological, as well as behavioral experiments.

If you are ambitious and striving to work in a highly motivated research environment with access to state of the art scientific instrumentation please contact us:

Research group "Experimental Neuropediatrics"
Center for Molecular Neurobiology Hamburg (ZMNH)
University Medical Center Hamburg-Eppendorf

Position available for one Diploma or MD student

We seek students with a strong interest in neuroscience and system biology. Our group uses a multidisciplinary approach (i.e., molecular biology, in vitro and in vivo electrophysiology, and behavioral biology) to investigate the molecular and cellular determinants of neuronal activity and network oscillations in the cortex and hippocampus, and their functional implications at the behavioral level. In particular, our research mainly focuses to the function of subthreshold-activating ion channels (e.g., IM) in specific neuronal subpopulations. Wild-type as well as appropriate inducible and conditional transgenic mice are used as animal models.
The successful candidate will be mainly involved in behavioral analyses, possibly in combination with pharmacological approaches, in vivo electrophysiological recordings or molecular analyses (depending on the interest of the student).

Literature:
Peters HC, Hu H, Pongs O, Storm JF, Isbrandt D (2005). Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. Nat Neurosci 8:51-60.
Jakovcevski M, Schachner M, Morellini F (2008). Individual variability in the stress response of C57BL/6J male mice correlates with trait anxiety. Genes Brain Behav 7:235-243.
Fellini L, Schachner M, Morellini F (2006). Adult but not aged C57BL/6 male mice are capable of using geometry for orientation. Learn Mem 13:473-481.
Morellini F, Schachner M (2006). Enhanced novelty-induced activity, reduced anxiety, delayed resynchronization to daylight reversal and weaker muscle strength in tenascin-C-deficient mice. Eur J Neurosci 23:1255-1268.

In addition to nice colleagues, we offer a throughout individually tailored training in behavioral neuroscience, a highly stimulating scientific environment, regular seminar sessions during which projects, own data and literature are discussed, as well as lectures presented by the principal investigators on theoretical and methodological issues relevant in the field of system biology and that are usually not covered by classical undergraduate programs (e.g., cognitive neuroscience, neuroethology, in vivo and in vitro electrophysiology, descriptive and inferential statistics …).

We expect high curiosity, motivation to learn and, indeed, very good mood.

Contact: Dr. Fabio Morellini, Experimental Neuropediatrics, UKE/ZMNH, Martinistraße 52, 20246 Hamburg, Germany. E-mail:

The University of Hamburg seeks to increase the number of female scientists and encourages them to apply. Disabled people with equal qualifications are preferred.
 
© ZMNH, University of Hamburg, Imprint