We seek highly motivated young researcher with interest in neurobiology, molecular biology, biochemistry, genetics and/or electrophysiology.
There are several ongoing projects regarding the physiological function of dopaminergic neurons in the midbrain which can be picked up by master or PhD students. Dopaminergic neurons are altered in disease such as Morbus Parkinson and drug addiction. Our lab obtained exciting data from cell culture and unique transgenic mouse models suggesting a strong influence of cell surface receptors on the development and progression of these diseases which can be studied now in great detail.
The ZMNH offers an excellent environment to study neurobiological questions with a multitude of different techniques supported by a modern infrastructure and several service groups. Special benefits can be offered for foreign students.
Please send
your application (preferentially by e-mail) to:
PD
Dr. Edgar Kramer
"Development and maintenance of
the nervous system"
ZMNH, Falkenried 94
20251 Hamburg, Germany .
E-mail:
; Tel: 040 741055354; Fax: 040 741055359;
Homepage
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Literature:
- Kramer ER*, Knott L*, Su F, Dessaud E, Krull C, Helmbacher F, and Klein R (2006). Cooperation between GDNF/Ret and ephrinA/EphA4 Signals for Motor-Axon Pathway Selection in the Limb. Neuron 50: 35-47.
- Kramer ER, Aron L, Ramaker GMJ, Seitz S, Zhuang X, Beyer K, Smidt MP and Klein R (2007). Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol. 5: 616-628.
- Ertürk A, Mauch CP, Hellal F, Förstner F, Keck T, Becker K, Jährling N, Steffens H, Richter M, Hübener M, Kramer E, Kirchhoff F, Dodt HU, Bradke F (2011). Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nat Med. 18(1):166-71.
- Gonzalez-Reyes LE, Verbitsky M, Blesa J, Jackson-Lewis V, Paredes D; Tillack K, Phani S, Kramer ER, Przedborski S, Kottmann AH (2012) Trophic signalling involving Sonic Hedgehog maintains the adult nigrostriatal circuit. Neuron 75: 306-319.
The University of Hamburg seeks to increase the number of female scientists and encourages them to apply. Disabled people with equal qualifications are preferred.

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